Scanners for the digitization of entire glass slides and the creation of whole slide images (also referred to as digital slides or virtual slides) are well established in the field of digital pathology. However, digital pathology (also termed virtual microscopy or virtual pathology) involves much more than just the creation, management, sharing, viewing, and interpretation of digital images. A real advantage of digital pathology is its ability to speed up quantification and diagnosis tasks by automated image analysis.
Software Development and Image Analysis Services
This is where microDimensions comes into play. Digital pathologists in pharmaceutical research, contract research organizations, and biotech companies value microDimensions’ services for customized and automated image analysis in e.g. drug discovery, toxicology studies, and companion diagnostics. From providing results (such as scoring) from image data to fully fledged applications with intuitive user interfaces, microDimensions has the expertise to develop and provide software solutions and services that can be tailored to and seamlessly integrated into current workflows. Our team of expert computer scientists, mathematicians, and biochemists has in-depth knowledge of
- image acquisition, reading, processing, segmentation, registration, and visualization,
- tissue analysis,
- the histology workflow,
- digital pathology systems and platforms,
- user interface and user experience design.
We collaborate with all major manufacturers of slide scanners and digital pathology systems to provide solutions which are independent of your hardware or infrastructure and ready for immediate use.
Are you interested in what we can do for your digital pathology workflow? Would you like to outsource your image analysis tasks? Please contact us for individual consultations, offers, and pricing.
VOLUME QUANTIFICATION FOR MOUSE MODELS IN OSTEOARTHRITIS RESEARCH
Developed for Merck KGaA, Germany
Software-based quantification highly labor-intensive, 35% of overall process time needed
> 30% speed-up for quantification using microDimensions‘ solution
Rigid image registration of patches at landmark positions
Developed for Definiens AG, Germany
Alignment of multi-stained sections required for image analysis, but inaccurate/labor-intensive with current solution
Significant speed-up in image analysis, improved communication with pathology clients
Spatial Alignment of entire virtual slides
Developed for a big biotech company, USA
Spatial alignment of existing commercial software is only accurate on small patches of whole slide image
Improved quality of image analysis - combination of biomarkers on 40x instead of 5x