Digital Pathology
Scanners for the digitization of entire glass slides and the creation of whole slide images (also referred to as digital slides or virtual slides) are well established in the field of digital pathology. However, digital pathology (also termed virtual microscopy or virtual pathology) involves much more than just the creation, management, sharing, viewing, and interpretation of digital images. A real advantage of digital pathology is its ability to speed up quantification and diagnosis tasks by automated image analysis.
Software Development and Image Analysis Services
This is where microDimensions comes into play. Digital pathologists in pharmaceutical research, contract research organizations, and biotech companies value microDimensions’ services for customized and automated image analysis in e.g. drug discovery, toxicology studies, and companion diagnostics. From providing results (such as scoring) from image data to fully fledged applications with intuitive user interfaces, microDimensions has the expertise to develop and provide software solutions and services that can be tailored to and seamlessly integrated into current workflows. Our team of expert computer scientists, mathematicians, and biochemists has in-depth knowledge of
- image acquisition, reading, processing, segmentation, registration, and visualization,
- tissue analysis,
- the histology workflow,
- digital pathology systems and platforms,
- user interface and user experience design.
We collaborate with all major manufacturers of slide scanners and digital pathology systems to provide solutions which are independent of your hardware or infrastructure and ready for immediate use.
Are you interested in what we can do for your digital pathology workflow? Would you like to outsource your image analysis tasks? Please contact us for individual consultations, offers, and pricing.
Success Stories
VOLUME QUANTIFICATION FOR MOUSE MODELS IN OSTEOARTHRITIS RESEARCH
Developed for Merck KGaA, Germany
- Pain:
Software-based quantification highly labor-intensive, 35% of overall process time needed - Gain:
> 30% speed-up for quantification using microDimensions‘ solution
“The stereology solution from microDimensions speeds up our workflow by more than 30 percent in comparison to our previous software solution. We are extremely happy with its streamlined workflow as well as intuitive user interface and value microDimensions’ very responsive support team.”
Rigid image registration of patches at landmark positions
Developed for Definiens AG, Germany
- Pain:
Alignment of multi-stained sections required for image analysis, but inaccurate/labor-intensive with current solution - Gain:
Significant speed-up in image analysis, improved communication with pathology clients
“The co-registration functionality of microDimensions’ technology is unrivaled in terms of speed and accuracy. Using the cutting-edge algorithms of microDimensions incorporated into Definiens’ Tissue Phenomics technology will considerably accelerate our phene discovery process for immune-mediated cancer therapies.”
Spatial Alignment of entire virtual slides
Developed for a big biotech company, USA
- Pain:
Spatial alignment of existing commercial software is only accurate on small patches of whole slide image - Gain:
Improved quality of image analysis - combination of biomarkers on 40x instead of 5x
“Compared to other software for co-registration, the accuracy and robustness of microDimensions’ alignment technology is unmatched, especially when we move on a high magnification level. Due to the high level of automation [...] we can significantly speed up our studies and create more significant readouts.”